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This is what my group does.
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--ci 0.95: Add--ci 0.95forassoc_qtwith PLINK2 data #25 - Selecting SNPs,
--snps rs16991615, added, extended at Let 'select_snps' work on 'assoc_qt_data' #41 -
--maf 0.01 -
--out /proj/nobackup/sens2017538/UKBB
Reading covariates works somewhat in plinkr, AFAIR the names are supplied with the .covar file:
* [ ] `--covar /proj/nobackup/sens2017538/UKBB_41143_Ppiller/covar_200507.txt`
* [ ] `--covar-name AGE_NORM AGE_NORM2 AGE_NORM3 AGE_NORM4 BMI array PC1 PC2 PC3 PC4 PC5 PC6 PC7 PC8 PC9 PC10 SMOKE MENO OC HYSTER NRBIRTH TDI`
I can only guess what this does:
* [ ] `--geno 0.05`
plinkr can do --glm (assoc_qt for PLINK2), but does not support the part after --glm
* [ ] `--glm hide-covar cols=+a1freq,+ax`
Some easier ones:
* [ ] `--hwe 1e-20`
* [ ] `--keep /proj/sens2017538/nobackup/UKBB_IMP_DOSAGE_V3/IDs_to_indlude_NonRelCauc.ukb41143.20191202.txt`
* [ ] `--keep-females`
File management using both PLINK binary and PLINK2 binary works. Here they use a mixed construct:
* [x] `--pgen /proj/sens2017538/nobackup/UKBB_IMP_DOSAGE_V3_bim_bed/chr20.pgen`
* [x] `--psam /proj/sens2017538/nobackup/UKBB_IMP_DOSAGE_V3/ukb41143.fam`
* [x] `--pvar /proj/sens2017538/nobackup/UKBB_IMP_DOSAGE_V3_bim_bed/chr20.bim`
Reading phenotypes works in plinkr, yet these are supplied with the .phe file:
* [x] `--pheno /proj/nobackup/sens2017538/UKBB_41143_Ppiller/phe_osteo_bmd.txt`
* [x] `--pheno-name OC`
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