diff --git a/src/dicomweb_client/file.py b/src/dicomweb_client/file.py
index f02b982..612c1f1 100644
--- a/src/dicomweb_client/file.py
+++ b/src/dicomweb_client/file.py
@@ -3127,6 +3127,7 @@ def retrieve_instance(
             '1.2.840.10008.1.2.4.91': 'application/dicom',
             '1.2.840.10008.1.2.4.92': 'application/dicom',
             '1.2.840.10008.1.2.4.93': 'application/dicom',
+            '1.2.840.10008.1.2.5': 'application/dicom',
         }
 
         supported_media_type_lut = {
@@ -3142,6 +3143,7 @@ def retrieve_instance(
                 '1.2.840.10008.1.2.4.91',
                 '1.2.840.10008.1.2.4.92',
                 '1.2.840.10008.1.2.4.93',
+                '1.2.840.10008.1.2.5',
                 '*',
             },
         }
diff --git a/tests/test_file.py b/tests/test_file.py
index 6b4d82c..0094e0e 100644
--- a/tests/test_file.py
+++ b/tests/test_file.py
@@ -248,6 +248,15 @@ def test_retrieve_instance(file_client):
     assert isinstance(instance, Dataset)
 
 
+def test_retrieve_instance_rle(file_client):
+    instance = file_client.retrieve_instance(
+        '1.2.826.0.1.3680043.8.498.12406831542731051035295345080039845114',
+        '1.2.826.0.1.3680043.8.498.16157229083793556332623330502397121062',
+        '1.2.826.0.1.3680043.8.498.49043964482360854182530167603505525116',
+    )
+    assert isinstance(instance, Dataset)
+
+
 def test_retrieve_instance_with_default_media_type(file_client):
     instance = file_client.retrieve_instance(
         '1.3.6.1.4.1.5962.1.1.0.0.0.1196530851.28319.0.1',