The Rosetta Bio-macromolecule modeling package.

Improved antibody structure-based design using inverse folding

This repo contains the codes for our paper "End-to-End Full-Atom Antibody Design"

This repo contains the codes for our paper Conditional Antibody Design as 3D Equivariant Graph Translation.

The official implementation of DiffAbXL benchmarked in the paper "Exploring Log-Likelihood Scores for Ranking Antibody Sequence Designs", formerly titled "Benchmarking Generative Models for Antibody Design".

Codes for our paper "UniMoMo: Unified Generative Modeling of 3D Molecules for De Novo Binder Design" (ICML 2025)

This is the official repository of paper - GeoAB: Towards Realistic Antibody Design and Reliable Affinity Maturation (ICML2024)

An antibody-specific language model focusing on NGL prediction

A Collection of Platform, Tools, and Resources for Antibody Engineering

structural antibody parser and database

The official implementation of "Improving Antibody Humanness Prediction using Patent Data".

Protein design with infilling language models and reinforcement learning — for antibodies and beyond.

PD-1 Targeted Antibody Discovery Using AI Protein Diffusion

Gradient guided discrete walk-jump sampling

Associated code/pipeline for the publication "AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications"

Integer Linear Programming for Protein Library Design

Code for ADIOS: Antibody Development via Opponent Shaping

Antibody optimization platform

Code for AAAI 2025 paper "Relation-Aware Equivariant Graph Networks for Epitope-Unknown Antibody Design and Specificity Optimization"

🦋 peleke-1: Protein Language Models for Targeted Antibody Design